PRP - My Cells - Facial Rejuvenation
March 2010
● The general public are just starting to become aware of this biostimulation technique for facial rejuvenation ... but it is commonly used by A list celebrities
● PRP is a technique where your own platelets are used to regenerate aged and damaged skin, reduce fine lines and wrinkles.
● At present this established method is already used in the fields of,
Dentistry
Neurosurgery
Wound healing
Orthopaedics
Plastic surgery
What is PRP ?
Your blood contains
Plasma
Red blood cells- 93%
White blood cells- 1%
Platelets- 6%
The function of these constituents of your blood are:-
■ Plasma- This is made of water and is a transport medium for your blood constituents.
■ White blood cells- Fight infection
■ Red blood cells- Carry oxygen to the cells
■ Platelets- Help in blood clotting. Help in building of new tissue and revascularisation of injured tissue ie: stimulates new collagen formation.
■ The white blood cells/red blood cells and platelets are of different weights and sizes, so it is possible to seperate them into seperate portions by using a centrifuge.
The red blood cells are the heaviest and sink to the bottom.
■ The PRP is a sophisticated technique which extracts the platelets out of the blood without the other blood cells (white and red blood cells). It is super concentrated platelets.
Platelets- Why use them for facial rejuvenation
They contain growth factors which heal and repair tissue, ideal for old, damaged skin and reduce fine lines and wrinkles.
These are:
♦ PDGF (platelet-derived growth factor)
♦ TGF-ß (transforming growth factor)
♦ VEGF (vascular endothelial growth factor)
♦ EGF (epithelial growth factor)
♦ IGF (insulin-like growth factor)
♦ PRP also includes fibrin, fibronectin and vitronectin, which are proteins known to act as cell adhesion molecules.
How is PRP prepared at the clinic your blood is taken ?
It is placed in a centrifuge
Specialised blood tubes are used in the centrifuge to extract the platelets.
Advantages of PRP Release of growth factors
■ Attract stem cells
■ Encourage stem cell proliferation / differentiation
■ Increase tissue regeneration
■ Decrease inflammation
■ Increase collagen
■ Increase bone density
PRP can be used in conjunction with:
Laser therapy
Skin needling ( Derma roller therapy)
Microdermabrasion and peels
It can be combined with various dermal fillers to obtain even better results.
Contra-indications of PRP
Low platelet counts
Bleeding disorders
Chronic liver problems
Smoking
Acute chronic infections
